/dev/ttyUSB0 missing after upgrade to bullseye

[/RaspberryPi]

What I have : Raspberry Pi 3 Model B Rev 1.2
What's it running : Linux piholeled 5.15.52-v7+ #1570 SMP Mon Jul 4 13:29:14 BST 2022 armv7l GNU/Linux, PRETTY_NAME="Raspbian GNU/Linux 11 (bullseye)"
What I'm doing with it : Using a Prolific Technology, Inc. PL2303 Serial Port / Mobile Action MA-8910P USB -> Serial cable to control an LED sign, using a Python program I wrote myself.
Bus 001 Device 005: ID 067b:2303 Prolific Technology, Inc. PL2303 Serial Port / Mobile Action MA-8910P
What's Wrong : Yesterday I upgraded from Buster to Bullseye. After dealing with a bucketload of problems I have just about everything in order , only one problem remains and my google-fu has failed me.
After the upgrade /dev/ttyUSB0 has vanished. This is what was called by the Python program to send data to the sign. When the program runs it returns :
serial.serialutil.SerialException: [Errno 2] could not open port /dev/ttyUSB0: [Errno 2] No such file or directory: '/dev/ttyUSB0'
A look at /dev shows this to be true, there is no /dev/ttyUSB0.
dmesg offered up :
[ 4.152219] usb 1-1.4: new full-speed USB device number 4 using dwc_otg [ 4.284552] usb 1-1.4: New USB device found, idVendor=067b, idProduct=2303, bcdDevice= 3.00 [ 4.284591] usb 1-1.4: New USB device strings: Mfr=1, Product=2, SerialNumber=0 [ 4.284611] usb 1-1.4: Product: USB-Serial Controller [ 4.284628] usb 1-1.4: Manufacturer: Prolific Technology Inc.
Things I have tried : Reboots Enabling Serial via raspi-config ( 5,p6,No, Yes ) Enabling I2C via raspi-config ( 5,p5,yes) Disconnecting / reconnecting adapter
This was working under Buster for several years. I'm not sure where to go from here. Suggestions ?

submitted by /u/Delchi
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